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Product Name
Armenian Hamster Anti-Mouse CD80 mAb (PE/TR)
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Gene ID
12519
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SwissProt ID
Q00609
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Gene Name
Mouse CD80
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Alternative Names
T-lymphocyte activation antigen CD80; Cd80; Activation B7-1 antigen; B7
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Background
CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
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Research Field
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Product Categories
Flowcytometry
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Host
Armenian Hamster
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Reactivity
Mouse
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Application
FC
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Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
16-10A1
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Isotype
IgG
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Immunogen
A synthesized peptide derived from Mouse CD80
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Purification
Affinity Purified
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Conjugation
PE/TR
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
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Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.