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Product Name
Mouse Anti-Human CD95 mAb (PE)
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Gene ID
355
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SwissProt ID
P25445
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Gene Name
FAS
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Alternative Names
FAS; ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6
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Background
CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.
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Research Field
Tags & Cell Markers
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Product Categories
Flowcytometry
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Host
Mouse
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Reactivity
Human
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Application
FC
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Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
4D11-G10
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Isotype
IgG1
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Immunogen
A synthesized peptide derived from Human FAS
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Purification
Affinity Purified
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Conjugation
PE
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
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Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.