产品详情
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Product Name
Syrian Hamster Anti-Mouse/Human KLRG-1 mAb (APC)
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Gene ID
10219/50928
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SwissProt ID
Q96E93/O88713
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Gene Name
Mouse/Human KLRG-1
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Alternative Names
MAFA; 2F4-Ag
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Background
Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+and CD4+cells, including CD4+and CD8+effector/memory cells, potent regulatory CD4+T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG6 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.
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Research Field
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Product Categories
Flowcytometry
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Host
Syrian Hamster
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Reactivity
Human,Mouse
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Application
FC
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Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
2F1
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Isotype
IgG
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Immunogen
A synthesized peptide derived from Human KLRG-1
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Purification
Affinity Purified
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Conjugation
APC
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
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Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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