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Product Name
Mouse Anti-Human CD4 mAb (FITC)
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Gene ID
920
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SwissProt ID
P01730
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Gene Name
CD4
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Alternative Names
CD4; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; CD antigen CD4
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Background
Swiss-Prot Acc.P01730.This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
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Research Field
Immunology
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Product Categories
Flowcytometry
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Host
Mouse
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Reactivity
Human
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Application
FC
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Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
4E11-G7
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Isotype
IgG2b
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Immunogen
A synthesized peptide derived from Human CD4
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Purification
Affinity Purified
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Conjugation
FITC
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
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Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.