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Product Name
ERBB2(D769Y Mutant) Mouse mAb
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SwissProt ID
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Gene Name
ERBB2,HER2,Neu,c-Neu
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Alternative Names
ERBB2,HER2,Neu,c-Neu
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Background
The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb-B gene-like family, encodes a transmembrane tyrosine kinase receptor that mediates extracellular signals activated by epidermal growth factors. Her2 abnormal has been strongly associated with many malignant tumors, especially with breast cancers. The expression level of Her2 is an important criteria in clinic evaluating of the progression of breast cancer.
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Research Field
Tags & Cell Markers
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Vertebrates
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Application
IHC-P, ICC/IF, ELISA
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Dilution Ratio
ELISA: 1/1000-1/2000 ICC/IF: 1/500-1/1000 IHC-P: 1/50-1/100
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Clonality
Monoclonal Antibody
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Clonality No.
9H2-S1-J2
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Isotype
IgG
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Immunogen
A synthetic peptide from the internal region of ERBB2 which includes the mutation of D769Y, human origin.
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Purification
Purified from ascites
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
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Storage
Store at -20°C. Avoid repeated freezing and thawing