货号: MT10072
别名: IDH2, D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH
应用: WB, IHC-P, ICC/IF, ELISA
反应种属: Vertebrates
目录价格:
RMB(含税报价)
数量: - + (库存件)
查看代理商 预计货期:3-4个工作日 说明书PDF
产品详情
  • Product Name
    IDH2(R172S Mutant) Mouse mAb
  • SwissProt ID
    ­
  • Gene Name
    IDH2, D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH
  • Alternative Names
    IDH2, D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH
  • Background
    Isocitrate dehydrogenase (IDH) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. The isocitrate and isopropylmalate dehydrogenases family has three members, IDH1, IDH2 and IDH3. IDH2 plays a role in intermediary metabolism and energy production. Defects in IDH2 are the cause of D-2-hydroxyglutaric aciduria type 2 (D2HGA2). Somatic mosaic mutations of this protein have also been found associated to Ollier disease and Maffucci syndrome, and R172S IDH2 mutations do exist in diffusely infiltrative gliomas.
  • Research Field
    Signal Transduction
  • Product Categories
    Primary antibody
  • Host
    Mouse
  • Reactivity
    Vertebrates
  • Application
    WB, IHC-P, ICC/IF, ELISA
  • Dilution Ratio
    ELISA: 1/1000-1/5000 WB: 1/100-1/1000 ICC/IF: 1/50-1/100
  • Clonality
    Monoclonal Antibody
  • Clonality No.
    7I2-G8-U5
  • Isotype
    IgG
  • Immunogen
    A synthetic peptide from the internal region of IDH2 which includes the mutation of R172S, human origin.
  • Purification
    Purified from ascites
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
  • Storage
    Store at -20°C. Avoid repeated freezing and thawing
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用,请参照上方的缩写含义,仔细对照后选择合适的产品。
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