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Product Name
JAK2(R683G Mutant) Mouse mAb
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SwissProt ID
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Gene Name
JAK2, JTK10, THCYT3
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Alternative Names
JAK2, JTK10, THCYT3
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Background
JAK2 is a non-receptor tyrosine kinase. It is a number of the Janus kinase family and has been implicated in signaling by members of the type II cytokine receptor family, the GM-CSF receptor family, the gp130 receptor family, and the single chain receptors. JAK2 orthologs have been identified in all mammals for which complete genome genome data are available. Mutations of JAK2 have been implicated in polycythemia vera, essential thrombocythemia, and myelofibrosis as well as other myeloproliferative disorders.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Vertebrates
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Application
WB, IHC-P,ELISA
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Dilution Ratio
ELISA: 1/1000-1/2000 WB: 1/500-1/1000 IHC-P: 1/50-1/100
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Clonality
Monoclonal Antibody
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Clonality No.
5S4-L9-Z9
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Isotype
IgG
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Immunogen
A synthetic peptide from the internal region of JAK2 which includes the mutation of R683G, human origin.
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Purification
Purified from ascites
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
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Storage
Store at -20°C. Avoid repeated freezing and thawing