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Product Name
Mouse Anti-Human HLA-DR mAb (EV450)
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Gene ID
3122/3123
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SwissProt ID
P01903/P01911
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Gene Name
HLA-DRA/HLA-DRB1
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Alternative Names
HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain; MHC class II antigen DRA; HLA-DRA1/DRB1; DRA/DRB1
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Background
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.
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Research Field
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Product Categories
Flowcytometry
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Host
Mouse
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Reactivity
Human
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Application
FC
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Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
L243
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Isotype
IgG2a
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Immunogen
A synthesized peptide derived from Human HLA-DR
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Purification
Affinity Purified
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Conjugation
EV450
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
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Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.