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Product Name
NFE2L2(D77V Mutant) Mouse mAb
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SwissProt ID
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Gene Name
NFE2L2, NRF2
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Alternative Names
NFE2L2, NRF2
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Background
NFE2L2 protein is encoded by NFE2L2 gene. It is a basic leucine zipper protein that regulates the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation. Several drugs that stimulate the NFE2L2 pathway are being studied for treatment of diseases that are caused by oxidative stress.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Vertebrates
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Application
IHC-P, ICC/IF, ELISA
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Dilution Ratio
ELISA: 1/1000-1/2000 ICC/IF: 1/50-1/100 IHC-P: 1/50-1/100
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Clonality
Monoclonal Antibody
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Clonality No.
6B6-T9-B1
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Isotype
IgG
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Immunogen
A synthetic peptide from the internal region of NFE2L2 which includes the mutation of D77V, human origin.
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Purification
Purified from ascites
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
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Storage
Store at -20°C. Avoid repeated freezing and thawing