产品详情
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Product Name
IRAK4 (2H9) Mouse mAb
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Gene ID
51135
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SwissProt ID
Q9NWZ3
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Gene Name
IRAK4
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Alternative Names
IL-1 receptor-associated kinase 4; Interleukin 1 receptor associated kinase 4 mutant form 1; IPD1; IRAK4; LOC 51135; NY REN 64; REN64
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Background
Required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human,Mouse,Monkey
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Application
WB,IHC-P,FC
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 52 kDa; Observed MW: 52 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
2H9-F11
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Isotype
IgG1
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Immunogen
Purified recombinant fragment of human IRAK4 expressed in E. Coli.
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Purification
Ascitic Fluid
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Ascitic fluid containing 0.03% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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