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Product Name
Ephrin Receptor A2 (7B3) Mouse mAb
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Gene ID
1969
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SwissProt ID
P29317
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Gene Name
EPHA2
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Alternative Names
EPHA2; ECK; Ephrin type-A receptor 2; Epithelial cell kinase; Tyrosine-protein kinase receptor ECK
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Background
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.
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Research Field
Cardiovascular
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200
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Molecular Weight
Calculated MW: 108 kDa; Observed MW: 120 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
7B3-10H7-7D9
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Isotype
IgM
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Immunogen
Purified recombinant fragment of EphA2 expressed in E. Coli.
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Purification
Ascitic Fluid
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Ascitic fluid containing 0.03% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.