产品详情
-
Product Name
KLHL1 Mouse mAb
-
Gene ID
57626
-
SwissProt ID
Q9NR64
-
Gene Name
KLHL1
-
Alternative Names
MRP2; FLJ30047; KIAA1490; KLHL1
-
Background
The mammalian Kelch like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin organizing proteins. Based on the presence of anti sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved in this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.Tissue specificity: Highly expressed in brain.
-
Research Field
Signal Transduction
-
Product Categories
Primary antibody
-
Host
Mouse
-
Reactivity
Human
-
Application
ICC/IF
-
Dilution Ratio
IF: 1/50-1/200
-
Molecular Weight
-
-
Clonality
Monoclonal Antibody
-
Clonality No.
3A8
-
Isotype
IgG1
-
Immunogen
Purified recombinant fragment of human KLHL1 expressed in E. Coli.
-
Purification
Ascitic Fluid
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Ascitic fluid containing 0.03% sodium azide.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。