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Product Name
Prostate Specific Antigen Mouse mAb
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Gene ID
354
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SwissProt ID
P07288
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Gene Name
KLK3
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Alternative Names
KLK3; APS; Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase
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Background
PSA/KLK3 is a member of the glandular kallikrein subfamily of serine proteases. Upon cleavage of 7 amino-terminal amino acids, it is activated to liquefy semen in the seminal coagulum. Although PSA/KLK3 is produced in healthy individuals, investigators have found abnormally high levels in the blood of men with advanced prostate cancer.
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,FC
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Dilution Ratio
WB: 1/500-1/1000 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 29 kDa; Observed MW: 37 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
8A12
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Isotype
IgG1
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Immunogen
Purified recombinant fragment of human KLK3 expressed in E. Coli.
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Purification
Ascitic Fluid
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.