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Product Name
Cytokeratin 17 (8C6) Mouse mAb
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Gene ID
3872
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SwissProt ID
Q04695
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Gene Name
KRT17
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Alternative Names
Keratin; type I cytoskeletal 17; Cytokeratin-17; CK-17; Keratin-17; K17
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Background
Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,IHC-P,ICC/IF,IP
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
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Molecular Weight
Calculated MW: 48 kDa; Observed MW: 48 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
8C6-4H2-5C1
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Isotype
IgG1
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Immunogen
Synthetic Peptide of CK17
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.