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Product Name
ALDH1L1 Mouse mAb
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Gene ID
10840
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SwissProt ID
O75891
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Gene Name
ALDH1L1
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Alternative Names
FDH; FTHFD; 10-fTHF; 10-FTHFDH
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Background
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P,FC,ELISA
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200 FC: 1/50-1/100 ELISA: 1/10000
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Molecular Weight
Calculated MW: 99kDa;Observed MW: 99kDa
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Clonality
Monoclonal Antibody
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Clonality No.
5R6-X2-U3
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Isotype
Mouse IgG1
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Immunogen
Purified recombinant fragment of human ALDH1L1 expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.