产品详情
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Product Name
NLRP6 Rabbit pAb
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Gene ID
171389
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SwissProt ID
P59044
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Gene Name
NLRP6
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Alternative Names
AVR; NAVR; PAN3; NALP6; PYPAF5; CLR11.4; NAVR/AVR
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Background
The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from inTinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
IHC-P
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Dilution Ratio
IHC: 1/50-1/100
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Molecular Weight
-
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Clonality
Polyclonal Antibody
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Clonality No.
-
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Isotype
IgG
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Immunogen
Synthetic peptide of human NLRP6
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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样本种属：
Human
杂 志：
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
应用：
IHC
IF：
2.8
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