-
Product Name
Caldesmon Mouse mAb
-
Gene ID
800
-
SwissProt ID
Q05682
-
Gene Name
CALD1
-
Alternative Names
CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22
-
Background
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
-
Research Field
Cell Biology
-
Product Categories
Primary antibody
-
Host
Mouse
-
Reactivity
Human,Mouse,Rat
-
Application
WB,IHC-P,ELISA
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200 ELISA: 1/10000
-
Molecular Weight
Calculated MW: 93 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
7J7-L4-C9
-
Isotype
Mouse IgG1
-
Immunogen
Purified recombinant fragment of human CALD1 expressed in E. Coli.
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Purified antibody in PBS with 0.05% sodium azide
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.