产品详情
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Product Name
CD163 Mouse mAb
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Gene ID
9332
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SwissProt ID
Q86VB7
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Gene Name
CD163
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Alternative Names
M130; MM130; SCARI1
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Background
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human,Mouse
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Application
WB,IHC-P,ELISA
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200 ELISA: 1/10000
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Molecular Weight
Calculated MW: 125 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
9H9-H6-W6
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Isotype
Mouse IgG1
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Immunogen
Purified recombinant fragment of human CD163 expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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