货号： 222238
别名： DBX; DDX3; HLP2; DDX14; CAP-Rf
应用： WB,IHC-P,ICC/IF,FC,ELISA
反应种属： Human,Rat,Mouse,Monkey
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    DDX3 Mouse mAb
  • Gene ID
    1654
  • SwissProt ID
    O00571
  • Gene Name
    DDX3X
  • Alternative Names
    DBX; DDX3; HLP2; DDX14; CAP-Rf
  • Background
    The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.
  • Research Field
    Epigenetics and Nuclear Signaling
  • Product Categories
    Primary antibody
  • Host
    Mouse
  • Reactivity
    Human,Rat,Mouse,Monkey
  • Application
    WB,IHC-P,ICC/IF,FC,ELISA
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200 FC: 1/50-1/100 ELISA: 1/10000
  • Molecular Weight
    Calculated MW: 73 kDa;Observed MW: 73 kDa
  • Clonality
    Monoclonal Antibody
  • Clonality No.
    6R1-V8-S4
  • Isotype
    Mouse IgG2a
  • Immunogen
    Purified recombinant fragment of human DDX3X expressed in E. Coli.
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Purified antibody in PBS with 0.05% sodium azide
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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