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Product Name
EPHB4 Mouse mAb
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Gene ID
2050
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SwissProt ID
P54760
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Gene Name
EPHB4
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Alternative Names
HTK; MYK1; TYRO11
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Background
EphB4: EPH receptor B4, also known as Htk, Myk1, Tyro11. Entrez Protein: NP_004435. It is a member of the Eph receptor family, which bind the ephrin ligand family. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The EphB4 protein binds to ephrin-B2 and plays an essential role in vascular development.
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Research Field
Cardiovascular
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 108 kDa;Observed MW: 72 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
8H7-P1-F1
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Isotype
Mouse IgG1
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Immunogen
Purified recombinant extracellular fragment of human EPHB4 fused with hIgGFc tag expressed in HEK293 cell line.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Ascitic fluid containing 0.03% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.