产品详情
-
Product Name
Granzyme B Mouse mAb
-
Gene ID
3002
-
SwissProt ID
P10144
-
Gene Name
GZMB
-
Alternative Names
C11; HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1
-
Background
This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]
-
Research Field
Cell Biology
-
Product Categories
Primary antibody
-
Host
Mouse
-
Reactivity
Human
-
Application
IHC-P,ELISA
-
Dilution Ratio
IHC: 1/100-1/200 ELISA: 1/10000
-
Molecular Weight
-
-
Clonality
Monoclonal Antibody
-
Clonality No.
3Y4-N6-E1
-
Isotype
Mouse IgG2a
-
Immunogen
Purified recombinant fragment of human GZMB expressed in E. Coli.
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Purified antibody in PBS with 0.05% sodium azide
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。