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Product Name
HDAC4 Mouse mAb
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Gene ID
9759
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SwissProt ID
P56524
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Gene Name
HDAC4
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Alternative Names
HD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A
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Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
ICC/IF,FC,ELISA
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Dilution Ratio
IF: 1/50-1/200 FC: 1/50-1/100 ELISA: 1/10000
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
1U3-H4-F1
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Isotype
Mouse IgG1
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Immunogen
Purified recombinant fragment of human HDAC4 expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.