货号： 222323
别名： HIF1; MOP1; PASD8; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF1A
应用： WB,IHC-P,ICC/IF,ELISA
反应种属： Human,Mouse,Monkey
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    HIF1 alpha Mouse mAb
  • Gene ID
    3091
  • SwissProt ID
    Q16665
  • Gene Name
    HIF1A
  • Alternative Names
    HIF1; MOP1; PASD8; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF1A
  • Background
    Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. (provided by RefSeq) Tissue specificity: Expressed in most tissues with highest levels in kidney and heart. Overexpressed in the majority of common human cancers and their metastases, due to the presence of intratumoral hypoxia and as a result of mutations in genes encoding oncoproteins and tumor suppressors.
  • Research Field
    Cardiovascular
  • Product Categories
    Primary antibody
  • Host
    Mouse
  • Reactivity
    Human,Mouse,Monkey
  • Application
    WB,IHC-P,ICC/IF,ELISA
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200 ELISA: 1/10000
  • Molecular Weight
    Calculated MW: 93 kDa
  • Clonality
    Monoclonal Antibody
  • Clonality No.
    5J5-M4-X6
  • Isotype
    Mouse IgG1
  • Immunogen
    Purified recombinant fragment of human HIF1A expressed in E. Coli.
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Ascitic fluid containing 0.03% sodium azide.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
引用文献 更多完整详情
用户反馈
    推荐排序
  • 最近评价
  • 推荐排序
产品评论
评论内容：
商品评分
  • ★
  • ★
  • ★
  • ★
  • ★
微信扫码关注
Copyright ©2022 - 2023 成都正能生物技术有限责任公司
蜀ICP备13012294号-2
川公网安备 51012202001504号
  网站地图
犀牛云提供企业云服务