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货号： 381335

别名： MGC22487; Oct 3; Oct 4; Oct-3; Oct-4; OCT3; Oct4; Octamer binding protein 3; Octamer binding protein 4; Octamer binding transcription factor 3; Octamer-binding protein 3; Octamer-binding protein 4; Octamer-binding transcription factor 3; OTF 3; OTF 4; OTF-3; OTF3; OTF4; PO5F1_HUMAN; POU class 5 homeobox 1; POU domain class 5 transcription factor 1; POU domain transcription factor OCT4; POU domain; class 5; transcription factor 1; POU5F1.

应用： WB,IHC-P,ICC/IF,IP,ChIP

反应种属： Human,Mouse

目录价格：

RMB(含税报价)

数量： - + （库存件）

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产品详情

Product Name

Oct-4 Rabbit pAb
Gene ID

5460
SwissProt ID

Q01860
Gene Name

POU5F1
Alternative Names

MGC22487; Oct 3; Oct 4; Oct-3; Oct-4; OCT3; Oct4; Octamer binding protein 3; Octamer binding protein 4; Octamer binding transcription factor 3; Octamer-binding protein 3; Octamer-binding protein 4; Octamer-binding transcription factor 3; OTF 3; OTF 4; OTF-3; OTF3; OTF4; PO5F1_HUMAN; POU class 5 homeobox 1; POU domain class 5 transcription factor 1; POU domain transcription factor OCT4; POU domain; class 5; transcription factor 1; POU5F1.
Background

Oct-4 is a transcription factor highly expressed in undifferentiated embryonic stem cells and embryonic germ cells. Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Research Field

Epigenetics and Nuclear Signaling
Product Categories

Primary antibody
Host

Rabbit
Reactivity

Human,Mouse
Application

WB,IHC-P,ICC/IF,IP,ChIP
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 ChIP: 1/20
Molecular Weight

Calculated MW: 39 kDa; Observed MW: 45 kDa
Clonality

Polyclonal Antibody
Clonality No.

-
Isotype

IgG
Immunogen

A synthesized peptide derived from human Oct4
Purification

Affinity Chromatography
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

标题： Primordial Dwarfism Gene Maintains Lin28 Expression to Safeguard Embryonic Stem Cells from Premature Differentiation

样本种属： Mouse

杂志： Cell Reports

应用： IF

IF： 7.207

文献链接

标题： AT7867 Inhibits the Growth of Colorectal Cancer Stem-Like Cells and Stemness by Regulating the Stem Cell Maintenance Factor Ascl2 and Akt Signaling

样本种属： Human

杂志： Stem Cells International

应用： WB

IF： 5.131

文献链接

标题： FK866 inhibits colorectal cancer metastasis by reducing NAD+ levels in cancer-associated fibroblasts

样本种属： Rabbit

杂志： Genes & Genomics

应用： WB

IF： 2.16

文献链接