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Product Name
Jagged 1 Mouse mAb
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Gene ID
182
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SwissProt ID
P78504
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Gene Name
CD339
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Alternative Names
JAG1; AGS; AHD; AWS; HJ1; AGS1; JAGL1
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Background
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,FC,ELISA
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Dilution Ratio
WB: 1/500-1/1000 FC: 1/50-1/100 ELISA: 1/10000
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Molecular Weight
Calculated MW: 134 kDa;Observed MW: 134 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
8R4-V6-Z9
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Isotype
Mouse IgG1
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Immunogen
Purified recombinant fragment of human CD339 expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.