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Product Name
JAK2 (7H5) Mouse mAb
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Gene ID
3717
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SwissProt ID
O60674
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Gene Name
JAK2
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Alternative Names
JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
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Background
Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human,Rat,Mouse
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Application
IHC-P
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Cited
WB (Mouse)
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Dilution Ratio
IHC: 1/50-1/100
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Molecular Weight
-
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Clonality
Monoclonal Antibody
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Clonality No.
7H5-1H1-5D10
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Isotype
IgG1
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Immunogen
Synthetic peptide conjugated to KLH.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.