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Product Name
CD127 Mouse mAb
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Gene ID
3575
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SwissProt ID
P16871
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Gene Name
CD127
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Alternative Names
IL7R; ILRA; IL7RA; CDW127; IL-7R-alpha
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Background
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,FC,ELISA
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Dilution Ratio
WB: 1/500-1/1000 FC: 1/50-1/100 ELISA: 1/10000
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Molecular Weight
Calculated MW: 52 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
8F9-J7-O7
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Isotype
Mouse IgG2b
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Immunogen
Purified recombinant fragment of human CD127 expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.