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Product Name
CD20 Mouse mAb
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Gene ID
931
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SwissProt ID
P11836
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Gene Name
CD20
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Alternative Names
B1; S7; Bp35; CD20; MS4A2; LEU-16; MGC3969; MS4A1
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Background
CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
IHC-P,ICC/IF
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Dilution Ratio
IHC: 1/100-1/200 IF: 1/50-1/200
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
1O4-E1-K4
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Isotype
Mouse IgG
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Immunogen
Synthetic peptide of human CD20,conjugated to KLH.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Ascitic fluid containing 0.03% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.