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Product Name
CD81 Mouse mAb
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Gene ID
975
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SwissProt ID
P60033
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Gene Name
CD81
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Alternative Names
S5.7; CVID6; TAPA1; TSPAN28
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Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.
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Research Field
Tags & Cell Markers
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human,Rat
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Application
WB,IHC-P,FC,ELISA
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200 FC: 1/50-1/100 ELISA: 1/10000
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Molecular Weight
Calculated MW: 26 kDa;Observed MW: 25-35 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
7W1-J2-R6
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Isotype
Mouse IgG1
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Immunogen
Purified recombinant fragment of human CD81 expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.