产品详情
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Product Name
CD8a Mouse mAb
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Gene ID
925
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SwissProt ID
P01732
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Gene Name
CD8a
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Alternative Names
CD8; p32; Leu2
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Background
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,FC,ELISA
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Dilution Ratio
WB: 1/500-1/1000 FC: 1/50-1/100 ELISA: 1/10000
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Molecular Weight
Calculated MW: 26 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
8H1-T9-T1
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Isotype
Mouse IgG1
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Immunogen
Purified recombinant fragment of human CD8a expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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