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Product Name
Hsp70 1A (2D4) Mouse mAb
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Gene ID
3303
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SwissProt ID
P0DMV8
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Gene Name
HSPA1A
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Alternative Names
HSP72; HSPA1; HSP70I; HSPA1B; HSP70-1; HSP70-1A.
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Background
In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 70 kDa; Observed MW: 70 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
2D4-F7-C11
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Isotype
IgG1
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Immunogen
Purified recombinant human Hsp70(N-terminus) protein fragments expressed in E.coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.