产品详情
-
Product Name
PKR Mouse mAb
-
Gene ID
5610
-
SwissProt ID
P19525
-
Gene Name
EIF2AK2
-
Alternative Names
PKR; PRKR; EIF2AK1
-
Background
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
-
Research Field
Signal Transduction
-
Product Categories
Primary antibody
-
Host
Mouse
-
Reactivity
Human
-
Application
WB,FC,ELISA
-
Dilution Ratio
WB: 1/500-1/1000 FC: 1/50-1/100 ELISA: 1/10000
-
Molecular Weight
Calculated MW: 62 kDa;Observed MW: 62 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
9M1-V1-E3
-
Isotype
Mouse IgG1
-
Immunogen
Purified recombinant fragment of human EIF2AK2 expressed in E. Coli.
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Purified antibody in PBS with 0.05% sodium azide.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。