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Product Name
Placental Alkaline Phosphatase Mouse mAb
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Gene ID
250
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SwissProt ID
P05187
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Gene Name
ALPP
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Alternative Names
ALP; PALP; PLAP; FLJ61142; ALPP
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Background
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
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Research Field
Tags & Cell Markers
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200
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Molecular Weight
Calculated MW: 58 kDa;Observed MW: 70 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
4P6-Y5-T9
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Isotype
Mouse IgG2b
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Immunogen
Purified recombinant fragment of human ALPP expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Ascitic fluid containing 0.03% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.