货号： 222684
别名： PDHA; PDHAD; PHE1A; PDHCE1A
应用： WB,IHC-P,ICC/IF,FC,ELISA
反应种属： Human,Mouse,Rat
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    PDHA1 Mouse mAb
  • Gene ID
    5160
  • SwissProt ID
    P08559
  • Gene Name
    PDHA1
  • Alternative Names
    PDHA; PDHAD; PHE1A; PDHCE1A
  • Background
    The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Research Field
    Signal Transduction
  • Product Categories
    Primary antibody
  • Host
    Mouse
  • Reactivity
    Human,Mouse,Rat
  • Application
    WB,IHC-P,ICC/IF,FC,ELISA
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200 FC: 1/50-1/100 ELISA: 1/10000
  • Molecular Weight
    Calculated MW:44kDa
  • Clonality
    Monoclonal Antibody
  • Clonality No.
    5M8-M7-J9
  • Isotype
    Mouse IgG1
  • Immunogen
    Purified recombinant fragment of human PDHA1 expressed in E. Coli.
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Purified antibody in PBS with 0.05% sodium azide
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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