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Product Name
Ku80 (8H1) Mouse mAb
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Gene ID
7520
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SwissProt ID
P13010
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Gene Name
XRCC5
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Alternative Names
XRCC5; G22P2; X-ray repair cross-complementing protein 5; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair pr
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Background
Ku80 the 80-kilodalton subunit of the Ku complex, also known as ATP-dependant DNA helicase II. A single stranded DNA-dependent ATP-dependent helicase. It functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human,Monkey
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Application
WB,ICC/IF,IP,ChIP
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 ChIP: 1/20
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Molecular Weight
Calculated MW: 83 kDa; Observed MW: 86 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
8H1-C3-G10
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Isotype
IgG1
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Immunogen
Purified recombinant human Ku80 protein fragments expressed in E.coli
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.