-
Product Name
EGFR (5E9) Mouse mAb
-
Gene ID
1956
-
SwissProt ID
P00533
-
Gene Name
EGFR
-
Alternative Names
EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
-
Background
EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.
-
Research Field
Signal Transduction
-
Product Categories
Primary antibody
-
Host
Mouse
-
Reactivity
Human
-
Application
WB,IP
-
Dilution Ratio
WB: 1/500-1/1000 IP: 1/20
-
Molecular Weight
Calculated MW: 134 kDa; Observed MW: 170 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
5E9-10B8-8B9
-
Isotype
IgG1
-
Immunogen
Synthetic Peptide of EGFR
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.