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货号： 200588-2D9

别名： HDAC2; Histone deacetylase 2; HD2

应用： WB,ICC/IF

反应种属： Human,Mouse,Rat,Monkey

目录价格：

RMB(含税报价)

数量： - + （库存件）

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产品详情

Product Name

HDAC2 (2D9) Mouse mAb
Gene ID

3066
SwissProt ID

Q92769
Gene Name

HDAC2
Alternative Names

HDAC2; Histone deacetylase 2; HD2
Background

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA.
Research Field

Epigenetics and Nuclear Signaling
Product Categories

Primary antibody
Host

Mouse
Reactivity

Human,Mouse,Rat,Monkey
Application

WB,ICC/IF
Dilution Ratio

WB: 1/500-1/1000 IF: 1/50-1/200
Molecular Weight

Calculated MW: 55 kDa; Observed MW: 60 kDa
Clonality

Monoclonal Antibody
Clonality No.

2D9-F6-G7
Isotype

IgG2b
Immunogen

Purified recombinant human HDAC2 protein fragments expressed in E.coli.
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

标题： Butyrate, but not propionate, reverses maternal diet-induced neurocognitive deficits in offspring

样本种属： Mouse

杂志： PHARMACOLOGICAL RESEARCH

应用： WB

IF： 5.893

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