产品详情
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Product Name
C5AR2 Mouse mAb
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Gene ID
27202
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SwissProt ID
Q9P296
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Gene Name
C5AR2
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Alternative Names
C5L2; GPF77; GPR77
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Background
This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.
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Research Field
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,IHC-P,FC,ELISA
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200 FC: 1/50-1/100 ELISA: 1/10000
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Molecular Weight
Calculated MW: 36kDa;Observed MW: 36kDa
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Clonality
Monoclonal Antibody
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Clonality No.
2O6-W4-Z9
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Isotype
Mouse IgG2b
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Immunogen
Purified recombinant fragment of human C5AR2 expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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