产品详情
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Product Name
GLRB Mouse mAb
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Gene ID
2743
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SwissProt ID
P48167
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Gene Name
GLRB
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Alternative Names
HKPX2
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Background
This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
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Research Field
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
ICC/IF,FC,ELISA
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Dilution Ratio
IF: 1/50-1/200 FC: 1/50-1/100 ELISA: 1/10000
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
2O6-G9-E7
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Isotype
Mouse IgG2b
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Immunogen
Purified recombinant fragment of human GLRB expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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