货号： 340776
别名： NFKBIA; IKBA; MAD3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3
应用： WB,IHC-F,IHC-P,ICC/IF,ELISA
反应种属： Human,Mouse,Rat,Monkey
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：现货 说明书PDF
产品详情
  • Product Name
    Phospho-IKB alpha (Ser32/Ser36) Rabbit pAb
  • Gene ID
    4792
  • SwissProt ID
    P25963
  • Gene Name
    NFKBIA
  • Alternative Names
    NFKBIA; IKBA; MAD3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3
  • Background
    NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm.
  • Research Field
    Epigenetics and Nuclear Signaling
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human,Mouse,Rat,Monkey
  • Application
    WB,IHC-F,IHC-P,ICC/IF,ELISA
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
  • Molecular Weight
    Calculated MW: 36 kDa; Observed MW: 36 kDa
  • Clonality
    Polyclonal Antibody
  • Clonality No.
    -
  • Isotype
    IgG
  • Immunogen
    The antiserum was produced against synthesized peptide derived from human IkappaB-alpha around the phosphorylation site of Ser32/Ser36.
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Phosphorylated
  • Form
    Liquid
  • Buffer System
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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标 题： Hydrogel-Based Artificial Mucosa Restores Local Immune and Microbial Homeostasis for Treating Ulcerative Colitis
样本种属： Mouse
杂 志： ADVANCED FUNCTIONAL MATERIALS
应用： WB
IF： 19.924
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标 题： Sirt4 deficiency promotes the development of atherosclerosis by activating the NF-κB/IκB/CXCL2/3 pathway
样本种属： Mouse
杂 志： ATHEROSCLEROSIS
应用： IF,WB
IF： 6.847
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标 题： Different Dose of Sucrose Consumption Divergently Influences Gut Microbiota and PPAR-&gamma||/MAPK/NF-&kappa||B Pathway in DSS-Induced Colitis Mice
样本种属： Mouse
杂 志： Nutrients
应用： WB
IF： 6.706
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标 题： Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro
样本种属： Human
杂 志： PHYTOMEDICINE
应用： WB
IF： 6.656
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标 题： CGRP Regulates Nucleus Pulposus Cell Apoptosis and Inflammation via the MAPK/NF-κB Signaling Pathways during Intervertebral Disc Degeneration
样本种属： Human
杂 志： Oxidative Medicine and Cellular Longevity
应用： WB
IF： 6.543
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标 题： Ulinastatin Ameliorates IL-1β-Induced Cell Dysfunction in Human Nucleus Pulposus Cells via Nrf2/NF-κB Pathway
样本种属： Human
杂 志： Oxidative Medicine and Cellular Longevity
应用： WB
IF： 6.543
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标 题： The Ameliorative Role of Lico A on Aflatoxin B1-Triggered Hepatotoxicity Partially by Activating Nrf2 Signal Pathway
样本种属： Mouse
杂 志： JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
应用： WB
IF： 6.1
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标 题： Gamabufotalin Inhibits Osteoclastgenesis and Counteracts Estrogen-Deficient Bone Loss in Mice by Suppressing RANKL-Induced NF-κB and ERK/MAPK Pathways
样本种属： Mouse
杂 志： Frontiers in Pharmacology
应用： WB
IF： 5.811
文献链接
标 题： Impact of chronic cold exposure on lung inflammation, pyroptosis and oxidative stress in mice
样本种属： Mouse
杂 志： INTERNATIONAL IMMUNOPHARMACOLOGY
应用： WB
IF： 5.7
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标 题： Protective effect of the total flavonoids from Clinopodium chinense against LPS-induced mice endometritis by inhibiting NLRP3 inflammasome-mediated pyroptosis
样本种属： Mouse
杂 志： JOURNAL OF ETHNOPHARMACOLOGY
应用： IF,WB
IF： 5.195
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标 题： Modulation of LPS-induced inflammation in RAW264.7 murine cells by novel isoflavonoids from Millettia pulchra
样本种属： Mouse
杂 志： BIOORGANIC CHEMISTRY
应用： WB
IF： 4.831
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标 题： Ursolic acid protects chondrocytes, exhibits anti-inflammatory properties via regulation of the NF-κB/NLRP3 inflammasome pathway and ameliorates osteoarthritis
样本种属： Rat
杂 志： BIOMEDICINE & PHARMACOTHERAPY
应用： WB
IF： 4.545
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标 题： Vericiguat Modulates Osteoclast Differentiation and Bone Resorption via a Balance between VASP and NF-κB Pathways
样本种属： Mouse
杂 志： MEDIATORS OF INFLAMMATION
应用： WB
IF： 4.529
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标 题： Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways
样本种属： Human
杂 志： JOURNAL OF ETHNOPHARMACOLOGY
应用： WB
IF： 4.36
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标 题： Safflower yellow alleviates osteoarthritis and prevents inflammation by inhibiting PGE2 release and regulating NF-κB/SIRT1/AMPK signaling pathways
样本种属： Rat
杂 志： PHYTOMEDICINE
应用： ICC
IF： 4.268
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标 题： Protective Effects of Phytic Acid on CCl4-Induced Liver Fibrosis in Mice
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杂 志： JOURNAL OF FOOD BIOCHEMISTRY
应用： WB
IF： 4
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标 题： CD5L induces inflammation and survival in RA-FLS through ERK1/2 MAPK pathway
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杂 志： AUTOIMMUNITY
应用： WB
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杂 志： JOURNAL OF CHEMICAL NEUROANATOMY
应用： WB
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