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Product Name
NUB1 Rabbit pAb
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Gene ID
51667
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SwissProt ID
Q9Y5A7
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Gene Name
NUB1
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Alternative Names
NEDD8 ultimate buster 1; Negative regulator of ubiquitin-like proteins 1; Renal carcinoma antigen NY-REN-18; NUB1; NYREN18
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Background
NEDD8 is a ubiquitin-like protein that controls vital biological events through its conjugation to cullin proteins. NEDD8 ultimate buster-1 (NUB1), is a negative regulator of the NEDD8 system that recruits NEDD8 and its conjugates to the proteasome for degradation. It is, therefore a cell growth regulator. The UBA domain of NUB1 is the specific acceptor for the linear ubiquitin precursor. NUB1 is composed of 601 amino acids. It is an interferon-inducible protein and predominantly localizes in the nucleus. NUB1 is specifically expressed in adult human testis, ovary, heart, and skeletal muscle tissues.
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Research Field
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB, IHC-P,IP
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/200 IP: 1/50-1/100
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Molecular Weight
Calculated MW: 70kDa
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Clonality
Polyclonal Antibody
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Clonality No.
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Isotype
IgG
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Immunogen
Synthetic peptide corresponding to Human NUB1.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.