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Product Name
Phospho-DDX5 (Tyr593) Rabbit pAb
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Gene ID
1655
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SwissProt ID
P17844
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Gene Name
DDX5
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Alternative Names
ATP dependent RNA helicase DDX5;
DDX 5;
Ddx5;
DDX5;
DEAD (Asp Glu Ala Asp) box helicase 5;
DEAD (Asp Glu Ala Asp) box polypeptide 5;
DEAD box 5;
DEAD box protein 5;
DEAD/H (Asp Glu Ala Asp/His) box polypeptide 5 (RNA helicase; 68kD);
DEAD/H (Asp Glu Ala Asp/His) box polypeptide 5;
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase 68kDa);
DEAD/H box-5 (RNA helicase 68kD);
DKFZp686J01190; G17P1;
HELR;
HLR 1;
HLR1;
HUMP68;
P68;
P68;
p68 RNA he
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Background
p68 RNA Helicase is a nuclear protein that exhibits RNA-dependent ATPase activity. Phosphorylation by protein kinase C inhibits p68 RNA Helicase activity. p68 RNA Helicase appears to play a role in organ differentiation during development. Furthermore, p68 RNA Helicase is expressed in early neural development and in various mesodermal tissues in a number of different chordate embryos. At the cellular level, the expression levels of p68 RNA Helicase increase in serum-induced quiescent cell lines. p68 RNA Helicase may function as a coactivator for estrogen receptor α. Additionally, p68 RNA Helicase associates with transcriptional coactivators CBP and p300. p68 RNA Helicase localizes to the nucleus under normal conditions. During late telophase, p68 RNA Helicase and fibrillarin co-localize to nascent nucleoli. p68 RNA Helicase may function as a heterodimer with p72 RNA Helicase.
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Research Field
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
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Clonality
Polyclonal Antibody
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Clonality No.
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Isotype
IgG
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Immunogen
Synthetic peptide derived from human p68 RNA Helicase around the phosphorylation site of Y593.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
Liquid
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Buffer System
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.