-
Product Name
PDE1B Mouse mAb
-
Gene ID
5153
-
SwissProt ID
Q01064
-
Gene Name
PDE1B
-
Alternative Names
PDE1B1; PDES1B; HEL-S-79p
-
Background
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
-
Research Field
Signal Transduction
-
Product Categories
Primary antibody
-
Host
Mouse
-
Reactivity
Human,Rat
-
Application
WB,IHC-P,FC
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200 FC: 1/50-1/100
-
Molecular Weight
Calculated MW: 61 kDa; Observed MW: 61 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
5G9
-
Isotype
IgG1
-
Immunogen
Purified recombinant fragment of human PDE1B expressed in E. Coli.
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Purified antibody in PBS with 0.05% sodium azide.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.