-
Product Name
Nrf2 (5F10) Mouse mAb
-
Gene ID
4780
-
SwissProt ID
Q16236
-
Gene Name
NFE2L2
-
Alternative Names
NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor; erythroid derived 2; like 2
-
Background
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
-
Research Field
Epigenetics and Nuclear Signaling
-
Product Categories
Primary antibody
-
Host
Mouse
-
Reactivity
Human
-
Application
WB,IHC-P
-
Cited
WB (Mouse)
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200
-
Molecular Weight
Calculated MW: 68 kDa; Observed MW: 68 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
5F10-G4-B3
-
Isotype
IgG1
-
Immunogen
Purified recombinant fragment of human NFE2L2 expressed in E. Coli.
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Purified antibody in PBS with 0.05% sodium azide.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.