产品详情
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Product Name
GPNMB Mouse mAb
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Gene ID
10457
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SwissProt ID
Q14956
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Gene Name
GPNMB
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Alternative Names
NMB; HGFIN
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Background
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,IHC-P
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Cited
WB (Mouse)
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200
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Molecular Weight
Calculated MW: 64 kDa; Observed MW: 64 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
7C10E5
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Isotype
IgG1
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Immunogen
Purified recombinant fragment of human GPNMB expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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样本种属：
Mouse
杂 志：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
应用：
WB
IF：
5.895
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