货号： 680367
别名： XRCC6_HUMAN; X-ray repair cross-complementing protein 6; G22P1; EC:3.6.4.-; EC:4.2.99.-; 5'-deoxyribose-5-phosphate lyase Ku70 (5'-dRP lyase Ku70); 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit (CTC75; CTCBF); ML8; KU70; KU-70; TLAA;
应用： WB
反应种属： Mouse,Rat
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    Ku70 / XRCC6 Rabbit pAb
  • Gene ID
    2547
  • SwissProt ID
    P12956
  • Gene Name
    XRCC6
  • Alternative Names
    XRCC6_HUMAN; X-ray repair cross-complementing protein 6; G22P1; EC:3.6.4.-; EC:4.2.99.-; 5'-deoxyribose-5-phosphate lyase Ku70 (5'-dRP lyase Ku70); 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit (CTC75; CTCBF); ML8; KU70; KU-70; TLAA;
  • Background
    It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together.
  • Research Field
    Epigenetics and Nuclear Signaling
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Mouse,Rat
  • Application
    WB
  • Dilution Ratio
    WB: 1/500-1/1000
  • Molecular Weight
    Calculated MW: 70kDa
  • Clonality
    Polyclonal Antibody
  • Clonality No.
    -
  • Isotype
    IgG
  • Immunogen
    KLH conjugated synthetic peptide derived from human Ku-70
  • Purification
    affinity purified by Protein A
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
  • Storage
    Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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