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Product Name
Leptin Rabbit pAb
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Gene ID
3952
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SwissProt ID
P41159
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Gene Name
LEP
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Alternative Names
LEP; Leptin Murine Obesity Homolog; Leptin Precursor Obesity Factor; OB; Obese Protein; Obesity; Obesity factor; Obesity homolog mouse; Obesity Murine Homolog Leptin; OBS; LEP_HUMAN.
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Background
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,ELISA
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Dilution Ratio
WB: 1/500-1/1000 ELISA: 1/5000-1/10000
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Molecular Weight
Calculated MW: 16kDa
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Clonality
Polyclonal Antibody
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Clonality No.
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Isotype
IgG
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Immunogen
Recombinant human Leptin
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Purification
affinity purified by Protein A
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.