-
Product Name
Phospho-HDAC3 (Ser424) Rabbit pAb
-
Gene ID
8841
-
SwissProt ID
O15379
-
Gene Name
HDAC3
-
Alternative Names
HDAC3 (phospho S424); HDAC3 (phospho Ser424); p-HDAC3 (Ser424); HDAC3_HUMAN; Histone deacetylase 3; EC:3.5.1.98; HD3; Protein deacetylase HDAC3; EC:3.5.1.; Protein deacylase HDAC3; RPD3-2; SMAP45; SMAP 45; SMAP-45; RPD3; KDAC3;
-
Background
HDAC3 is a nuclear and cytoplasmic protein that deacetylates both histone (H2A, H3, H4) and non-histone substrates (RelA, SRY, p53, MEF2, PCAF and p300/CBP). HDAC3 deacetylase activity is stimulated by interactions with the N-CoR and SMRT co-repressor proteins. Together, these three proteins form a functional complex that represses transcription associated with nuclear hormone receptors and other transcription factors, including Rev-Erb, COUP-TF, DAX1, MAD and Pit-1.
-
Research Field
Epigenetics and Nuclear Signaling
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Mouse,Rat
-
Application
WB,IHC-F,IHC-P,ICC/IF,FC,ELISA
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/5000-1/10000
-
Molecular Weight
Calculated MW: 47kDa
-
Clonality
Polyclonal Antibody
-
Clonality No.
-
-
Isotype
IgG
-
Immunogen
KLH conjugated Synthesised phosphopeptide derived from human HDAC3 around the phosphorylation site of Ser424
-
Purification
affinity purified by Protein A
-
Conjugation
Unconjugated
-
Modification
Phosphorylated
-
Form
Liquid
-
Buffer System
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
-
Storage
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.