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Product Name
HDAC7 Rabbit pAb
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Gene ID
51564
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SwissProt ID
Q8WUI4
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Gene Name
HDAC7
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Alternative Names
Histone deacetylase 7; EC:3.5.1.98; HDAC7A; HD7; Histone deacetylase 7A (HD7a); HDAC7_HUMAN.
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Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Mouse
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Application
WB,IHC-F,IHC-P,ICC/IF,ELISA
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/5000-1/10000
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Molecular Weight
Calculated MW: 105kDa
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Clonality
Polyclonal Antibody
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Clonality No.
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Isotype
IgG
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Immunogen
KLH conjugated synthetic peptide derived from human HDAC7
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Purification
affinity purified by Protein A
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.