货号： 680640
别名： P63_HUMAN; Tumor protein 63; TP63; Chronic ulcerative stomatitis protein (CUSP); Keratinocyte transcription factor KET; Transformation-related protein 63 (TP63); Tumor protein p73-like (p73L); p40; p51; KET; P63; P73H; P73L; TP73L; AIS; LMS; NBP; RHS; p40; p51; EEC3; OFC8; SHFM4; TP53L; p53CP; TP53CP; B(p51A); B(p51B); P51A; TAp63gamma; P51B; TAp63alpha; P51delta; TAp63delta; P51delNalpha; DeltaNp63 alpha; P51delNbeta; DeltaNp63 beta; P51delNgamma; DeltaNp63gamma; p40 - DeltaNp63; p40-DeltaNp63;
应用： IHC-F,IHC-P,ICC/IF,ELISA
反应种属： Human
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    Phospho-p63 (Ser455) Rabbit pAb
  • Gene ID
    8626
  • SwissProt ID
    Q9H3D4
  • Gene Name
    TP63
  • Alternative Names
    P63_HUMAN; Tumor protein 63; TP63; Chronic ulcerative stomatitis protein (CUSP); Keratinocyte transcription factor KET; Transformation-related protein 63 (TP63); Tumor protein p73-like (p73L); p40; p51; KET; P63; P73H; P73L; TP73L; AIS; LMS; NBP; RHS; p40; p51; EEC3; OFC8; SHFM4; TP53L; p53CP; TP53CP; B(p51A); B(p51B); P51A; TAp63gamma; P51B; TAp63alpha; P51delta; TAp63delta; P51delNalpha; DeltaNp63 alpha; P51delNbeta; DeltaNp63 beta; P51delNgamma; DeltaNp63gamma; p40 - DeltaNp63; p40-DeltaNp63;
  • Background
    Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis.
  • Research Field
    Cell Biology
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human
  • Application
    IHC-F,IHC-P,ICC/IF,ELISA
  • Dilution Ratio
    IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/5000-1/10000
  • Molecular Weight
    Calculated MW: 77kDa
  • Clonality
    Polyclonal Antibody
  • Clonality No.
    -
  • Isotype
    IgG
  • Immunogen
    KLH conjugated Synthesised phosphopeptide derived from human p63 around the phosphorylation site of Ser455
  • Purification
    affinity purified by Protein A
  • Conjugation
    Unconjugated
  • Modification
    Phosphorylated
  • Form
    Liquid
  • Buffer System
    0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
  • Storage
    Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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